Detalhe da pesquisa
1.
An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.
Cell
; 173(6): 1413-1425.e14, 2018 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29754815
2.
Anti-cancer therapy: senescence is the new black.
EMBO J
; 37(10)2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29669859
3.
Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis.
Nature
; 479(7371): 122-6, 2011 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21983962
4.
A proof-of-concept study of sequential treatment with the HDAC inhibitor vorinostat following BRAF and MEK inhibitors in BRAFV600mutated melanoma.
Clin Cancer Res
; 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38739109
5.
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.
PLoS One
; 17(9): e0273182, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36067171
6.
Genetic and compound screens uncover factors modulating cancer cell response to indisulam.
Life Sci Alliance
; 5(9)2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534224
7.
Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.
Mol Cancer Res
; 19(10): 1613-1621, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34158393
8.
The Cancer SENESCopedia: A delineation of cancer cell senescence.
Cell Rep
; 36(4): 109441, 2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320349
9.
With great power comes great vulnerability.
Mol Cell Oncol
; 5(6): e1509488, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525088
10.
A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma.
Eur Urol
; 71(6): 858-862, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28108151
11.
High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.
Cell Rep
; 21(3): 773-783, 2017 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045843
12.
The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts.
Cell Rep
; 12(6): 992-1005, 2015 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26235614
13.
Gene-targeting of Phd2 improves tumor response to chemotherapy and prevents side-toxicity.
Cancer Cell
; 22(2): 263-77, 2012 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22897855
14.
Growing tumor vessels: more than one way to skin a cat - implications for angiogenesis targeted cancer therapies.
Mol Aspects Med
; 32(2): 71-87, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21540050
15.
Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells.
J Mol Med (Berl)
; 87(6): 561-9, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19455291